Journal of Conservative Dentistry

ORIGINAL ARTICLE
Year
: 2022  |  Volume : 25  |  Issue : 3  |  Page : 241--245

Antioxidant, anti-inflammatory activity of Thymus vulgaris-mediated selenium nanoparticles: An in vitro study


Indumathy Pandiyan1, Sri Sakthi D1, Meignana Arumugham Indiran1, Pradeep Kumar Rathinavelu1, Jayashri Prabakar1, S Rajeshkumar2 
1 Department of Public Health Dentistry, Saveetha Dental College and Hospital, Chennai, Tamil Nadu, India
2 Department of Pharmacology, Saveetha Dental College and Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Sri Sakthi D
Department of Public Health Dentistry, Saveetha Dental College and Hospital, 162, Poonamalee High Road, Chennai - 600 077, Tamil Nadu
India

Background: Nanotechnology is the specialty associated with material science and biology, rather than a particular field. It entails the method of particles at nanoscale called Nanoparticles, wherein they have control over bulk macroscopic properties of the identical material. The “drug nanocarrier,” selenium possesses strong antibacterial, antioxidant and anti-cancer as well as anti-inflammatory properties. As the medicinal plant Thymus vulgaris possesses a lot of phytochemicals, this study was conducted to assess the anti-inflammatory and antioxidant activity of selenium nanoparticles (SeNps) reinforced with T. vulgaris. Materials and Methods: Anti-inflammatory activity, antioxidant activity of SeNps reinforced with T. vulgaris extract were assessed using bovine serum albumin and 2, 2-diphenyl-1-picrylhydrazyl assay, respectively, at 10, 20, 30, 40, and 50 μL. Results: The values for anti-inflammatory property of nanoparticles were higher than the standard values at 30, 40, and 50 μL concentrations. Percentage of inhibition was highest at 40 μL (87.7%) and 50 μL (92.6%). The values for antioxidant property of nanoparticles were found to be higher than the standard values at 10, 20, and 30 μL concentrations. Percentage of inhibition was highest at 30 μL (68.3%). Conclusion: SeNps reinforced with T. vulgaris extract have a potential as an anti-inflammatory and antioxidant agent and can be used as an alternative to commercially available products.


How to cite this article:
Pandiyan I, SriS, Indiran MA, Rathinavelu PK, Prabakar J, Rajeshkumar S. Antioxidant, anti-inflammatory activity of Thymus vulgaris-mediated selenium nanoparticles: An in vitro study.J Conserv Dent 2022;25:241-245


How to cite this URL:
Pandiyan I, SriS, Indiran MA, Rathinavelu PK, Prabakar J, Rajeshkumar S. Antioxidant, anti-inflammatory activity of Thymus vulgaris-mediated selenium nanoparticles: An in vitro study. J Conserv Dent [serial online] 2022 [cited 2022 Jul 4 ];25:241-245
Available from: https://www.jcd.org.in/article.asp?issn=0972-0707;year=2022;volume=25;issue=3;spage=241;epage=245;aulast=Pandiyan;type=0