| ORIGINAL ARTICLE |
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| Year : 2023 | Volume
: 26
| Issue : 2 | Page : 150-159 |
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Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste
Mithra N Hegde1, N Suchetha Kumari2, Nireeksha Shetty1, V Chaithra Lakshmi1, Nidarsh Divakar Hegde3, Nishmitha N Hegde3, Jyoti Singh4, Amit Sirdesai4, Prasun Bandyopadhyay5
1 Department of Conservative Dentistry and Endodontics, A. B. Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India
2 Department of Biochemistry, Central Research Laboratory, KSHEMA, Mangalore, Karnataka, India
3 Department of Conservative Dentistry and Endodontics, A. B. Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India
4 Research Scientist, R & D, Dabur India Ltd, Sahibabad, Ghaziabad, Uttar Pradesh, India
5 Global VP Home & Personal Care, Dabur India Ltd, Sahibabad, Ghaziabad, Uttar Pradesh, India
Correspondence Address:
Prof. Mithra N Hegde
A. B. Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore - 575 018, Karnataka
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jcd.jcd_542_22
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Objective: The objective of this study was to study the effect of medicated toothpaste on oral health, a 6-month follow-up.
Methods: Four hundred and twenty-seven participants were screened and followed up for 6 months. The intraoral examination was performed to record caries, gingival bleeding, and plaque index. Saliva collected was evaluated for pH, total antioxidant capacity (TAC), malondialdehyde (MDA), and Vitamin C level for 6 months, and data were analyzed.
Results: On the usage of medicated toothpaste with herbal extract for 6 months, the salivary pH levels were increased, the interquartile range for plaque, and the gingival bleeding index decreased. The percentage change in salivary TAC, MDA, and Vitamin C levels in the caries-free group of subgroup I was 174.8, 58.06, and 59.98, respectively, in subgroup II was 133.3, 52.08, and 58.51, and in subgroup III was 63.77, 45.11, and 47.77. The percentage change in salivary TAC, MDA, and Vitamin C levels in the caries-active group of subgroup I was 136.62, 57.27, and 72.83, subgroup II was 108.59, 37.50, and 61.55, and in subgroup III was 35.62, 30.82, and 54.10, respectively.
Conclusion: The salivary pH levels increased on the usage of medicated toothpaste with herbal extract; plaque and the gingival bleeding index scores were decreased. The salivary antioxidant defense was increased in individuals using medicated toothpaste with herbal extracts which signifies an improvement in overall oral health in the 6-month follow-up.
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