| ORIGINAL ARTICLE |
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| Year : 2020 | Volume
: 23
| Issue : 1 | Page : 15-20 |
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The effect of adding graphene oxide nanoplatelets to Portland cement: Potential for dental applications
Abubaker S Qutieshat1, Ahmad S Al-Hiyasat2, Mohammad R Islam3
1 Conservative Dentistry Department, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan; Unit of Cell and Molecular Biology, Dundee Dental School, University of Dundee, Dundee, Scotland, UK
2 Conservative Dentistry Department, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan
3 Unit of Cell and Molecular Biology, Dundee Dental School, University of Dundee, Dundee, Scotland, UK
Correspondence Address:
Dr. Abubaker S Qutieshat
Jordan University of Science and Technology, Irbid 22110
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/JCD.JCD_274_20
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Background: The potential of graphene-based materials to improve the physiomechanical properties of Portland cement-based materials without compromising biocompatibility is of interest to dental researchers and remains to be discovered.
Aim: This study investigated the effects of adding graphene oxide nanoplatelets (GONPs) on the surface microhardness and biocompatibility of Portland cement.
Materials and Methods: Three prototype Portland cement powder formulations were prepared by adding 0, 1, and 3 wt % GONPs in powder form to Portland cement. Prototype cement specimens were in the form of disks, with a diameter of 10 mm and a thickness of 2 mm. In experiment 1, surface microhardness was measured using the through indenter viewing hardness tester, 20 surface hardness values were obtained from all specimens. In experiment 2, Balb/C 3T3 fibroblasts were cultured with the material disks and the viability of cells was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.
Statistical Analysis: The data were analyzed using the analysis of variance followed by Dunnett test (α = 0.05) or Tukey test (α = 0.05).
Results: In response to material disks, the addition of 1 wt % GONPs had a proliferative effect on cells at day 3 and day 7 with a significant difference from the control. The addition of 3 wt % GONPs showed a remarkable increase in surface microhardness; however, it exhibited initial cytotoxicity.
Conclusions: The addition of 1 wt % GONPs to Portland cement improved surface microhardness without compromising biocompatibility; therefore, it has a greater potential for dental applications. The results of this work give other researchers leads in future assessments of this prototype material.
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