Journal of Conservative Dentistry
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Year : 2017  |  Volume : 20  |  Issue : 6  |  Page : 415-418

Grape seed extract: An innovation in remineralization

Department of Conservative Dentistry and Endodontics, Bharati Vidyapeeth Deemed University, Dental College, and Hospital, Sangli, Maharashtra, India

Correspondence Address:
Ketaki Dinkar Jawale
Bharati Vidyapeeth Deemed University, Dental College and Hospital, Wanlesswadi, Sangli-Miraj Road, Sangli, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JCD.JCD_287_16

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Aim: The aim of this study was to determine remineralizing potential of grape seed extract (GSE) compared to casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and calcium glycerophosphate (CaGP) through pH-cycling model and subsequent evaluation using polarized light microscope (PLM). Subjects and Methods: Twenty sound human teeth fragments of ten teeth were obtained from the cervical portion of the roots and were stored in demineralizing solution for 96 h at 37°C to induce artificial root carious lesion. The sections then were divided into four treatment groups including: 6.5% GSE, CPP-ACP, 0.5% CaGP, and control group (no treatment). The demineralized samples were then pH cycled through treatment solutions, acidic buffer, and neutral buffer for 8 days at six cycles per day. The samples were subsequently evaluated using PLM. Statistical Analysis Used: Data were analyzed using ANOVA and Scheffe post hoc comparison test (P < 0.001). Results: PLM data revealed a significantly thicker mineral precipitation band on the surface layer of the GSE-treated lesions compared to the other groups (P < 0.001). Conclusion: GSE positively affects the demineralization and/or remineralization processes of artificial root caries lesions.

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