|
In vitro comparison of antimicrobial effect of sodium hypochlorite solution and Zataria multiflora essential oil as irrigants in root canals contaminated with Candida albicans
Mahdi Sedigh-Shams1, Parisa Badiee2, Alireza Adl3, Milad Dadollahi Sarab4, Abbas Abbaszadegan1, Mohammadreza Nabavizadeh5
1 Department of Endodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
2 Department of Mycology, Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3 Department of Endodontics, Biomaterials Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
4 Student Research Committee, International Branch, Shiraz University of Medical Sciences, Shiraz, Iran
5 Department of Endodontics, Prevention of Oral and Dental Disease Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
Correspondence Address:
Dr. Alireza Adl
Department of Endodontics, School of Dentistry, Ghasrodasht Street, Shiraz
Iran
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0972-0707.173212
|
|
Introduction: This study compared the antifungal effect of Zataria multiflora essential oil (EO) with that of sodium hypochlorite (NaOCl) as an irrigant for root canals infected with Candida albicans.
Materials and Methods: Sixty mandibular premolars were infected with C. albicans suspension. After 72 h of incubation, the samples were divided into four groups. Teeth in Group 1 were irrigated with minimum fungicidal concentration (MFC) of Z. multiflora EO, in Group 2 with twice the MFC of Z. multiflora, in Group 3 with MFC of NaOCl, and in Group 4 with distilled water (DW). Pre- and post-operative samples were cultured, and fungal colony count of each specimen was obtained. Data were analyzed using Kruskal-Wallis and Mann-Whitney tests (P < 0.05).
Results: NaOCl at MFC and Z. multiflora EO at twice the MFC showed the highest antifungal efficacy, with no significant difference (P > 0.05). However, antifungal efficacies of these irrigants were significantly different from those of Z. multiflora EO at MFC and DW (P < 0.05).
Conclusion: Our results showed that Z. multiflora EO at twice the MFC had the same antifungal efficacy as NaOCl at MFC. |
