Journal of Conservative Dentistry
Home About us Editorial Board Instructions Submission Subscribe Advertise Contact e-Alerts Login 
Users Online: 6978
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size
Year : 2014  |  Volume : 17  |  Issue : 2  |  Page : 133-137

Comparative anti-microbial efficacy of Azadirachta indica irrigant with standard endodontic irrigants: A preliminary study

1 Department of Restorative Dentistry, Edinburgh Dental Institute, Lauriston Place, Edinburgh, EH3 8DA, Scotland, United Kingdom
2 Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Mangalore, Karnataka, India

Correspondence Address:
Arindam Dutta
Department of Restorative Dentistry, Edinburgh Dental Institute, Lauriston Building, Lauriston Place, Edinburgh, EH3 8DA, Scotland, United Kingdom

Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-0707.128047

Rights and Permissions

Objective: The anti-microbial efficacy of 2.5% sodium hypochlorite (SHC) and 0.2% chlorhexidine gluconate were compared with an experimental irrigant formulated from the Neem tree, Azadirachta indica A. Juss. Materials and Methods: A sample of 36 single rooted anterior teeth with periapical radiolucency and absence of response to vitality tests that required root canal treatment were selected for this study. The test irrigants and their combinations were assigned to five different groups and saline served as the control. Access cavities were prepared using an aseptic technique and samples collected for both anaerobic culture and Gram stained smears, followed by irrigation and sample collection again. The number of organisms were expressed in colony forming units/ml after 72 h of incubation; the smears were analyzed for their microbial loads and tissue clearance and assessed as per defined criteria. Results: Our results found the maximum reduction in microbial loads, when analyzed by culture method, with a combination of SHC and the experimental neem irrigant. Maximum tissue clearance on the Gram Stained smears was also found with the same combination. Conclusion: Neem irrigant has anti-microbial efficacy and can be considered for endodontic use.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded387    
    Comments [Add]    
    Cited by others 8    

Recommend this journal